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Phrases contain exact "severe asthma" from credible sources

EXACT :

There is high certainty that all approved biologicals reduce the rate of severe asthma exacerbations and for benralizumab, dupilumab and mepolizumab for reducing OCS. There is moderate certainty for improving asthma control, QoL, FEV 1. More data on long-term safety are needed together with more efficacy data in the paediatric population.
pubmed.ncbi.nlm.nih.gov


Patients with severe asthma frequently have radiological abnormalities on HRCT. Sensitization to A. fumigatus is associated with bronchiectasis and greater airflow obstruction, even when diagnostic criteria for ABPA are not met.
pubmed.ncbi.nlm.nih.gov


Primary care records of 17,278,392 adults were pseudonymously linked to 10,926 COVID-19-related deaths. COVID-19-related death was associated with: being male (hazard ratio (HR) 1.59 (95% confidence interval 1.53-1.65)); greater age and deprivation (both with a strong gradient); diabetes; severe asthma; and various other medical conditions.
pubmed.ncbi.nlm.nih.gov


The charity is calling for people with non-severe asthma to be prioritised ahead of their peers after the first nine groups have been vaccinated. "The government's lack of attention, urgency and ...
www.bbc.com


While I am not a sufferer of severe asthma (such patients require regular hospital visits and medication), I still take a steroid inhaler daily and have to carefully control my triggers to prevent ...
www.independent.co.uk


Dirty air is already known to increase hospital treatment for severe asthma attacks and other respiratory problems. But the new research is the first using clinical data to show increased illness ...
www.theguardian.com


That same year, Ella started to suffer terrifyingly severe asthma attacks. Finally, in February 2013, after about 30 of such attacks, Ella sadly died.
www.theguardian.com


Focus on your breathing, and match it with your pace as best you can. Be sure to carry an inhaler with you with you in case you have a severe asthma attack. Always stop if you're feeling faint, but push yourself to your breaking point if you can. Running is great for your lungs -- it strengthens the muscles.
www.wikihow.com


The purpose of this guideline is to maximise the safety of adults and children with severe asthma during the COVID-19 pandemic, while protecting staff from infection. It will also enable services to make the best use of NHS resources. This guideline focuses on what you need to stop or start doing during the pandemic.
www.nice.org.uk


Severe Asthma Burden. Approximately 3-10% of people with asthma have severe disease. In Australia, this represents between 52,800 and 176,000 people. Severe asthma is a serious problem that places a heavy burden on individuals and their families. People with severe asthma have frequent symptoms and attacks.
www.severeasthma.org.au


The ATS-ERS task force on Severe Asthma includes an updated definition of severe asthma, a discussion of severe asthma phenotypes in relation to genetics, natural history, pathobiology and physiology, as well as sections on evaluation and treatment of severe asthma where specific recommendations for practice were made.
www.thoracic.org


Severe asthma is not the same for everyone. So finding the right treatment options may take time and will differ from person to person. The goal of asthma treatment, like most medical treatment, is to achieve the best possible level of asthma control with the lowest amount of treatment. People with severe asthma tend to have more symptoms or ...
asthma.org.au


Patients newly prescribed mepolizumab for severe asthma with 12 months' relevant medical history pre-mepolizumab (collected retrospectively) were enrolled. An initial analysis of data from early initiators who had completed 1-year follow-up (as of 28 February 2019) was conducted.
pubmed.ncbi.nlm.nih.gov


A new Pocket Guide, “Diagnosis and Management of Difficult-to-treat and Severe Asthma in adolescent and adult patients” is now available on the GINA website, and print copies may be ordered via the “Contact Us” form on the website. Embracing the issue of severe asthma was a critical goal for the GINA Board of Directors and Science ...
ginasthma.org


Among children (aged 6 to 18 years) and adults with moderate to severe asthma, triple therapy, compared with dual therapy, was significantly associated with fewer severe asthma exacerbations and modest improvements in asthma control without significant differences in quality of life or mortality.
pubmed.ncbi.nlm.nih.gov


How does biologic therapy treat severe asthma? Asthma is a complex disease. Many patients are able to control asthma with inhaler therapy. But some patients with severe asthma have episodes of frequent symptoms and episodes where the asthma gets much worse even when they use more than one inhaler.
my.clevelandclinic.org


severe asthma where specific recommendations for practice are made. See the unabridged online version of the document for detailed discussion of the definition of severe asthma, phenotypes and recommendations for practice. When a diagnosis of asthma is confirmed and comorbidities have been addressed, severe asthma is defined
www.thoracic.org


Common symptoms are coughing, shortness of breath, wheezing and chest tightness. Asthma may lead to a medical emergency. It is important to know the signs of a severe asthma episode (or asthma attack). How Is Asthma Diagnosed? A doctor may use a few different ways of testing for asthma. These include: Taking a detailed medical history; A ...
www.aafa.org


Bronchial thermoplasty is a surgical technique used for severe asthma that hasn’t improved with other treatments. During this technique, radiofrequency energy is applied to the airway.
www.healthline.com


The Biologics License Application (BLA) for tezepelumab has been submitted to the Food and Drug Administration (FDA) for patients with severe asthma.
www.empr.com


Many severe asthma patients have an inadequate response to currently available biologics and oral corticosteroids and thus fail to achieve asthma control. 6-8 Uncontrolled asthma occurs when ...
www.prnewswire.com


Phrases contain similar "severe asthma" from credible sources

SIMILAR :

Among children (aged 6 to 18 years) and adults with moderate to severe asthma, triple therapy, compared with dual therapy, was significantly associated with fewer severe asthma exacerbations and modest improvements in asthma control without significant differences in quality of life or mortality.
pubmed.ncbi.nlm.nih.gov


Background: Mepolizumab and omalizumab are treatments for distinct but overlapping severe asthma phenotypes. Objective: To assess if patients eligible for both biologics but not optimally controlled with omalizumab experience improved asthma control when switched directly to mepolizumab. Methods: OSMO was a multicenter, open-label, single-arm, 32-week trial in patients with ≥2 asthma ...
pubmed.ncbi.nlm.nih.gov


Background: Some patients with severe asthma have frequent exacerbations associated with persistent eosinophilic inflammation despite continuous treatment with high-dose inhaled glucocorticoids with or without oral glucocorticoids. Methods: In this randomized, double-blind, double-dummy study, we assigned 576 patients with recurrent asthma exacerbations and evidence of eosinophilic ...
pubmed.ncbi.nlm.nih.gov


Methods: REALITI-A is a global, prospective, observational cohort study, collecting data from routine healthcare visits from patients with asthma. Patients newly prescribed mepolizumab for severe asthma with 12 months' relevant medical history pre-mepolizumab (collected retrospectively) were enrolled.
pubmed.ncbi.nlm.nih.gov


Methods: COLUMBA (Open-label Long Term Extension Safety Study of Mepolizumab in Asthmatic Subjects, NCT01691859) was an open-label extension study in patients with SEA previously enrolled in DREAM (Dose Ranging Efficacy And Safety With Mepolizumab in Severe Asthma, NCT01000506). Patients received 100 mg of subcutaneous mepolizumab every 4 weeks ...
pubmed.ncbi.nlm.nih.gov


Five biologicals have been approved for severe eosinophilic asthma, a well-recognized phenotype. Systematic reviews (SR) evaluated the efficacy and safety of benralizumab, dupilumab, mepolizumab, omalizumab and reslizumab (alphabetical order) compared to standard of care for severe eosinophilic asthma.
pubmed.ncbi.nlm.nih.gov


An EpiPen is an epinephrine auto-injector used to treat a severe allergic reaction called anaphylaxis. Anaphylaxis can be triggered by different allergies, including food, venom, and drug allergies.[v161496_b01]. 29 July 2020. Anaphylaxis...
www.wikihow.com


Risk factors for severe COVID-19 include older age, ethnicity, sex, comorbidities, and living conditions. Although asthmatics and those with allergies are susceptible to more severe outcomes to viral infections, interestingly, asthma has not been reported to be a major comorbidity of COVID-19.
pubmed.ncbi.nlm.nih.gov


Asthma can be classified into either intermittent or persistent, and the latter is either mild, moderate, or severe. Some patients change, in either direction, from intermittent to persistent asthma. In addition, patients with asthma may be classified as allergic (immunoglobulin E mediated), nonallergic (often triggered by viral upper ...
pubmed.ncbi.nlm.nih.gov


Soon after approval, severe allergic reactions to the mRNA-based vaccines that resolved after treatment were reported. Regulatory agencies from the European Union, Unites States and the United Kingdom agree that vaccinations are contraindicated only when there is an allergy to one of the vaccine components or if there was a severe allergic ...
pubmed.ncbi.nlm.nih.gov


Management of persistent asthma requires avoidance of aggravating environmental factors, use of short-acting β2-agonists for rapid relief of symptoms, and daily use of inhaled corticosteroids. Other controller medications, such as long-acting bronchodilators and biologics, may be required in moderate and severe asthma.
pubmed.ncbi.nlm.nih.gov


The pandemic of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused an unprecedented global social and economic impact, and high numbers of deaths. Many risk factors have been identified in the progression of COVID-19 into a sev …
pubmed.ncbi.nlm.nih.gov


Interpretation: In patients with uncontrolled moderate or severe asthma on ICS/LABA, adding UMEC improved lung function but did not lead to a significant reduction in moderate and/or severe exacerbations. For such patients, single-inhaler FF/UMEC/VI is an effective treatment option with a favourable risk-benefit profile.
pubmed.ncbi.nlm.nih.gov


Albuterol has been used for more than 40 years to treat acute asthma exacerbations as a racemic mixture of isomers: the active form, (R)-albuterol, or levalbuterol, and (S)-albuterol, classically considered inert. The single-isomer formulation, levalbuterol, has been synthesized recently and used th …
pubmed.ncbi.nlm.nih.gov


Asthma is a common disease with substantial human and economic costs globally. Although there is no cure or established means of prevention, effective treatment is available. Use of the recommendations in the 2020 Asthma Guideline Update should improve the health of individuals with asthma.
pubmed.ncbi.nlm.nih.gov


Allergic rhinitis (AR) was long considered a quite trivial disease, but the advance in epidemiological and clinical knowledge, with a major role for Allergic rhinitis and its Impact on Asthma (ARIA) initiative, substantially changed the scene. Now we know that AR has significant effects on patients …
pubmed.ncbi.nlm.nih.gov


Emotions do not directly cause asthma, but the changes in your rate and rhythm of breathing that accompany emotions can trigger an attack. Severe anxiety and actions like crying and yelling can affect your breathing and bring on an attack. Even emotional distress brought on by an attack itself can worsen your symptoms.
www.wikihow.com


Patients with asthma and COVID-19 were older and at increased risk due to comorbidity-related factors. ICS and biologics are generally safe and may be associated with a protective effect against severe COVID-19 infection.
pubmed.ncbi.nlm.nih.gov


Tiotropium add-on may have additional benefits over LABA/ICS alone in reducing the need for rescue oral steroids in people with severe asthma. The effect was imprecise, and there was no evidence for other LAMA preparations. Possible benefits on quality of life were negligible, and evidence for the e …
pubmed.ncbi.nlm.nih.gov


Background: Eosinophilic inflammation is frequently associated with increased asthma severity. Benralizumab is a humanized, afucosylated, anti-interleukin-5Rα monoclonal antibody that selectively depletes eosinophils and basophils through enhanced antibody-dependent cell-mediated cytotoxicity.
pubmed.ncbi.nlm.nih.gov


Severe asthma is not the same for everyone, so finding the right treatment options may take time and will differ from person to person. The goal of asthma treatment, like most medical treatment, is to achieve the best possible level of asthma control with the lowest amount of treatment. People with severe asthma tend to have more symptoms or ...
asthma.org.au


The ATS-ERS task force on Severe Asthma includes an updated definition of severe asthma, a discussion of severe asthma phenotypes in relation to genetics, natural history, pathobiology and physiology, as well as sections on evaluation and treatment of severe asthma where specific recommendations for practice were made.
www.thoracic.org


Overview. Asthma is an inflammatory lung disease that can lead to mild to severe symptoms. In most cases, you can control your asthma through avoiding triggers, daily medications and other ...
www.healthline.com


The purpose of this guideline is to maximise the safety of adults and children with severe asthma during the COVID-19 pandemic, while protecting staff from infection. It will also enable services to make the best use of NHS resources. This guideline focuses on what you need to stop or start doing during the pandemic.
www.nice.org.uk


Severe Asthma Burden. Approximately 3-10% of people with asthma have severe disease. In Australia, this represents between 52,800 and 176,000 people. Severe asthma is a serious problem that places a heavy burden on individuals and their families. People with severe asthma have frequent symptoms and attacks.
www.severeasthma.org.au


What’s different about severe asthma? Severe asthma is the most serious and life-threatening form of asthma. Most people with asthma can manage their symptoms well with the usual medicines like a preventer inhaler and a reliever inhaler. But someone with severe asthma struggles to manage their symptoms even with high doses of medicines.
www.asthma.org.uk


Status asthmaticus is the medical name for the most severe cases of acute asthma. Learn more about the symptoms, causes, diagnosis, treatment, and prevention of status asthmaticus.
www.webmd.com


Severe asthma is not the same for everyone. So finding the right treatment options may take time and will differ from person to person. The goal of asthma treatment, like most medical treatment, is to achieve the best possible level of asthma control with the lowest amount of treatment. People with severe asthma tend to have more symptoms or ...
asthma.org.au


Severe asthma patients use these medications in combination with quick-relief medicine, high-dose inhaled corticosteroids and long-acting bronchodilators. Side effects from using oral corticosteroids can pose a risk to the function of other bodily organs, but the benefits may at times outweigh the risk. The hope is that by using these powerful ...
www.lung.org


Risk of severe illness from COVID-19. People with moderate-to-severe or uncontrolled asthma are more likely to be hospitalized from COVID-19. Take steps to protect yourself. Protect yourself from COVID-19. Get a COVID-19 vaccine when it is available to you. Wear a mask that covers your nose and mouth.
www.cdc.gov


Maggie, 32, who lives in Edinburgh, Scotland, has borderline severe asthma, and is currently being investigated for an underlying autoimmune condition due to a series of kidney infections.
inews.co.uk


phone the Asthma advice line on 1800 44 54 64 and ask for an action plan; download an asthma action plan (PDF, 330KB, 2 pages) If you get COVID-19. You can usually treat symptoms of COVID-19 at home. But some people may need to be admitted to hospital. This decision will be made with your GP. It will depend on your:
www2.hse.ie


A 16 year old female with a history of severe asthma is brought to your community emergency department after a week of respiratory symptoms that have suddenly become much worse. She has been admitted to hospital 4 times this year, including one visit to the ICU.
first10em.com


Acute severe asthma, also known as status asthmaticus, is an acute exacerbation of asthma that does not respond to standard treatments of bronchodilators (inhalers) and corticosteroids. Asthma is caused by multiple genes, some having protective effect, with each gene having its own tendency to be influenced by the environment although a genetic link leading to acute severe asthma is still unknown.
en.wikipedia.org


A new Pocket Guide, “Diagnosis and Management of Difficult-to-treat and Severe Asthma in adolescent and adult patients” is now available on the GINA website, and print copies may be ordered via the “Contact Us” form on the website. Embracing the issue of severe asthma was a critical goal for the GINA Board of Directors and Science ...
ginasthma.org


Asthma Overview. Asthma affects more than 25 million Americans 1. It is a chronic disease that causes your airways to become inflamed, making it hard to breathe. There is no cure for asthma. The best way to manage asthma is to avoid triggers, take medications to prevent symptoms and prepare to treat asthma episodes if they occur.
www.aafa.org


severe asthma where specific recommendations for practice are made. See the unabridged online version of the document for detailed discussion of the definition of severe asthma, phenotypes and recommendations for practice. When a diagnosis of asthma is confirmed and comorbidities have been addressed, severe asthma is defined
www.thoracic.org


Around 17% of people with asthma have ‘difficult to control’ asthma. This means they have difficulty breathing almost all of the time and often have what could be life-threatening asthma attacks. More rarely, you may have a specific type of asthma called ‘severe asthma’. Only about 4% of people with asthma have ‘severe asthma’.
www.asthma.org.uk


A severe asthma attack is a potentially life-threatening event. Symptoms of a severe attack might be similar to the symptoms of a minor asthma attack.
www.healthline.com


The most important part of preventing severe asthma attacks is knowing you have the condition in the first place. Here are the top signs you have severe asthma, plus which kinds of treatment may help.
www.self.com



severe asthma

[səˈvɪr ˈæzmə]


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